Bio-RFID and Dielectric Spectroscopy

Emerging Technologies

Bio-RFID and dielectric spectroscopy represent promising approaches to non-invasive glucose monitoring.

Bio-RFID Technology

How It Works

• Uses radio frequency identification technology
• RF signals interact with tissue
• Glucose concentration affects signal characteristics

Potential Advantages

• Completely non-invasive
• No consumable sensors needed
• Continuous monitoring possible

Key Players

• Know Labs: Leading Bio-RFID development
• Multiple university research programs

Dielectric Spectroscopy

How It Works

• Measures tissue electrical properties
• Glucose affects dielectric constant of tissue
• Changes detected through impedance measurements

Approach Variations

• Microwave spectroscopy
• Impedance spectroscopy
• Multi-frequency analysis

Technical Challenges

Signal Clarity

• Glucose signal is small compared to noise
• Skin thickness variations affect readings
• Temperature and hydration impact measurements

Calibration

• Individual variation requires personalization
• Stability over time uncertain
• Reference measurements still needed

Current Status

Research Phase

• Academic studies showing correlation
• Early prototype devices
• No FDA-cleared products yet

Industry Activity

• Know Labs: Clinical trials ongoing
• Afon: Developing spectroscopy-based device
• Major tech companies (Apple, Samsung) exploring

The Path Forward

These technologies need to demonstrate:

• Accuracy comparable to invasive CGMs
• Reliability across diverse populations
• Long-term stability
• Practical form factors for daily use