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Calibration Algorithms and Factory-Calibration
Modern CGMs use sophisticated calibration algorithms, with many now featuring factory-calibration that eliminates the need for user fingerstick calibrations.
Calibration Algorithms and Factory-Calibration
The Role of Calibration
CGMs rely on calibration algorithms to translate raw sensor signals into accurate glucose readings.
Types of Calibration
User Calibration
Traditional approach requiring periodic fingerstick blood glucose measurements to adjust sensor readings.
Factory Calibration
Modern approach where sensors come pre-calibrated from manufacturing:
- Abbott's FreeStyle Libre pioneered this approach
- Dexcom G6/G7 use factory calibration
- No user calibration required
How Factory Calibration Works
Manufacturers test each sensor batch against reference standards and program calibration parameters into the sensor or transmitter.
Pros and Cons
Factory Calibration Advantages
- Convenience—no fingersticks needed
- Reduced user error
- Consistent performance from day one
Potential Drawbacks
- May lack the precision of individualized calibration
- Cannot account for individual physiological variations
- Some users prefer the control of manual calibration